Rekombinanter FOXP3 Antikörper (AA 275-325)

Produktnummer ABIN7795682

Dieser Kaninchen Monoklonal Antikörper erkennt spezifisch FOXP3 in WB, FACS und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter FOXP3 Antikörper (AA 275-325) (ABIN7795682)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FOXP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: BLR282M

Produktdetails anti-FOXP3 Antikörper

Bindungsspezifität: AA 275-325

Verwendungszweck: Rabbit anti-FOXP3 Recombinant Monoclonal Antibody [BLR282M]

Aufreinigung: Purified

Immunogen: Between 275 and 325

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IP,6 μL/mg lysate,WB,11000,Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 0.5 μL per 1 x 10^6 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Andere Bezeichnung: FOXP3

Hintergrund: FOXP3 is a transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). It plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. FOXP3 can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases.  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BZS1].

Gen-ID: 50943

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation